A practical guide to local employment, major employers, and job search resources in the Pee Dee region.
Whether you're already in Florence and looking for your next opportunity, or considering a move and wondering what the job market looks like — this page is your starting point. Florence is the economic hub of the Pee Dee region, home to major employers in healthcare, education, manufacturing, and government.
Florence serves as the employment center of the Pee Dee region, offering a diverse job market that punches above its weight for a city of its size. Located at the strategic intersection of I-95 and I-20, Florence has established itself as a regional hub for healthcare, logistics, manufacturing, retail, and education.
While Florence isn't a major metropolitan area, it offers something increasingly rare: a place where your paycheck stretches further. The lower cost of living means you're likely to afford more house, have a shorter commute, and actually have time for the things that matter — all without sacrificing access to the amenities that make day-to-day life comfortable.
💡 Pro tip: Compare salaries to Charlotte, Columbia, or the coast, and you'll find Florence offers competitive pay with a noticeably lower cost of living.
These are the largest and most consistent employers in the Florence area.
The region's dominant healthcare system and one of the largest employers in the Pee Dee. McLeod Regional Medical Center is a major hub for clinical, administrative, and support roles.
A four-year public university offering faculty, staff, and administrative positions. One of Florence's most stable employers with excellent benefits.
The primary public school district serving Florence County, with consistent openings in teaching, administration, and support roles year-round.
Municipal government jobs ranging from public works and parks to administration and public safety. Stable employment with municipal benefits.
County government positions across a wide range of departments. Opportunities include roles in administration, health services, and public works.
Major healthcare employer serving the Florence area and broader Pee Dee region. Now part of the MUSC Health network.
Florence has two Walmart Supercenter locations and a Sam's Club, all of which regularly hire across retail, pharmacy, logistics, and management roles.
The city's premier entertainment and events venue regularly seeks event, operations, and hospitality staff for concerts, conferences, and community events.
This list covers major anchor employers. Florence also has a strong small business community — local restaurants, shops, and service businesses are often hiring and may not post on major job boards. Ask around.
These are the most useful places to search for open positions in Florence and the surrounding Pee Dee region.
The primary workforce center serving Florence and the surrounding region. SC Works offers job listings, resume help, career coaching, interview prep, and free computer access.
Visit SC Works Pee DeeFilter by Florence, SC for the most current postings across all industries. Indeed aggregates listings from company career pages and other job boards.
Search Indeed JobsEspecially useful for professional, administrative, and management roles in Florence. Great for networking and building connections with local employers.
Browse LinkedIn JobsFor state government positions including agencies operating in Florence County. State jobs offer competitive benefits and pension plans.
Browse State JobsSouth Carolina's official workforce portal connecting job seekers with employers statewide. Includes training programs and career resources.
Visit WorkSCOpen to students and alumni of Francis Marion University, but also lists community job postings. A great resource even if you're not affiliated with FMU.
Visit FMU Career CenterFlorence is becoming an increasingly attractive option for remote workers. The city's lower cost of living, short commute times, and location within driving distance of major cities (Charlotte, Columbia, and the coast) make it an ideal base for distributed teams.
Downtown Florence has coffee shops with reliable WiFi — The Bean Bar is a local favorite for remote work. There are coworking options emerging, and the overall pace of life supports productivity without the distractions of a major metro.
Lower Cost of Living
More house for your money
Short Commutes
Minutes, not hours
Central Location
Easy drives to major cities
Florence has solid workforce development infrastructure for people looking to upskill or change careers.
Offers technical degrees, certifications, and workforce training programs across healthcare, IT, trades, and business. FDTC is the region's primary source for practical, job-ready skills.
Four-year degrees and graduate programs with strong ties to the local employer community. FMU offers day, evening, and online courses to fit working adults' schedules.
Free career coaching, resume help, and skills training for eligible job seekers. SC Works partners with local employers to provide training programs that lead directly to jobs.
Florence isn't a city where you come to coast. It's a city where your dollar goes further, your commute stays short, and you actually have time to build the life you're working toward. Whether you're job hunting, switching careers, or bringing your remote work here — the Pee Dee has room for you.
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