Florence, SC & the Pee Dee Region
Your Community Guide
29501 · The Community Hub
Florence has a growing economy anchored by healthcare, manufacturing, education, and logistics. Here is your guide to finding work in the Pee Dee region.
Growing
Pee Dee Economy
Top 5
SC Cities for Job Growth
4
Major Industry Sectors
29501
Where Careers Are Built
The largest and most established employers in Florence and the Pee Dee region.
Healthcare
The region's largest hospital and healthcare system, employing thousands in nursing, administration, and specialized medical roles.
View Open Positions →Education
A-rated school district employing teachers, administrators, bus drivers, and support staff across dozens of schools.
View Open Positions →Healthcare Technology
Leading manufacturer of medical equipment and healthcare technology, creating engineering and production jobs in Florence.
View Open Positions →Understanding where Florence's economy is strongest helps you position your career.
Largest employment sector in the Pee Dee, led by McLeod Health and MUSC Health Florence.
McLeod · MUSC · Community health centers
Growing sector with GE Healthcare and regional distribution centers driving new jobs.
GE Healthcare · UPS · Local manufacturers
Strong presence of public schools, universities, and technical colleges in Florence.
FMU · FDTC · School District 1
City, county, state, and federal employers provide stable employment opportunities.
City of Florence · Florence County · VA Hospital
Updated regularly. Positions across all major sectors in the Pee Dee.
For the most current job listings across all industries in Florence and the Pee Dee region, visit SC Works.
Browse All Jobs on SC Works →Training programs, certifications, and career development resources available right here in the Pee Dee.
Free career services including resume help, interview prep, job fairs, and job placement assistance for Florence residents.
Learn More →Short-term certifications, associate degrees, and workforce training programs designed around Florence's biggest industries.
Learn More →Career counseling, job board access, networking events, and employer connections for students and community members.
Learn More →Free career services including resume help, interview prep, and job placement assistance for Florence residents.
Free computer access, resume printing, LinkedIn workshops, and career resource guides.
Short-term certifications and workforce training programs designed around Florence's biggest industries.
Florence serves as the employment center of the Pee Dee region, offering a diverse job market that punches above its weight for a city of its size. Located at the strategic intersection of I-95 and I-20, Florence has established itself as a regional hub for healthcare, logistics, manufacturing, retail, and education.
While Florence isn't a major metropolitan area, it offers something increasingly rare: a place where your paycheck stretches further. The lower cost of living means you're likely to afford more house, have a shorter commute, and actually have time for the things that matter — all without sacrificing access to the amenities that make day-to-day life comfortable.
💡 Pro tip: Compare salaries to Charlotte, Columbia, or the coast, and you'll find Florence offers competitive pay with a noticeably lower cost of living.
These are the largest and most consistent employers in the Florence area.
The region's dominant healthcare system and one of the largest employers in the Pee Dee. McLeod Regional Medical Center is a major hub for clinical, administrative, and support roles.
A four-year public university offering faculty, staff, and administrative positions. One of Florence's most stable employers with excellent benefits.
The primary public school district serving Florence County, with consistent openings in teaching, administration, and support roles year-round.
Municipal government jobs ranging from public works and parks to administration and public safety. Stable employment with municipal benefits.
County government positions across a wide range of departments. Opportunities include roles in administration, health services, and public works.
Major healthcare employer serving the Florence area and broader Pee Dee region. Now part of the MUSC Health network.
Florence has two Walmart Supercenter locations and a Sam's Club, all of which regularly hire across retail, pharmacy, logistics, and management roles.
The city's premier entertainment and events venue regularly seeks event, operations, and hospitality staff for concerts, conferences, and community events.
GE has maintained a significant manufacturing presence in the Florence area, making it one of the region's most established industrial employers.
A global leader in scientific instrumentation and laboratory services with operations in the Florence area, offering technical, manufacturing, and support roles.
Located in nearby Timmonsville, Honda Manufacturing of South Carolina produces all-terrain vehicles and is one of the Pee Dee region's most significant manufacturing employers. Regularly hires for production, technical, and administrative roles.
Florence's location at the crossroads of I-95 and I-20 has made it a hub for distribution and logistics operations. QVC and other major distribution employers in the region regularly hire warehouse, operations, and logistics staff.
This list covers major anchor employers. Florence also has a strong small business community — local restaurants, shops, and service businesses are often hiring and may not post on major job boards. Ask around.
These are the most useful places to search for open positions in Florence and the surrounding Pee Dee region.
The primary workforce center serving Florence and the surrounding region. SC Works offers job listings, resume help, career coaching, interview prep, and free computer access.
Visit SC Works Pee DeeFilter by Florence, SC for the most current postings across all industries. Indeed aggregates listings from company career pages and other job boards.
Search Indeed JobsEspecially useful for professional, administrative, and management roles in Florence. Great for networking and building connections with local employers.
Browse LinkedIn JobsFor state government positions including agencies operating in Florence County. State jobs offer competitive benefits and pension plans.
Browse State JobsOpen to students and alumni of Francis Marion University, but also lists community job postings. A great resource even if you're not affiliated with FMU.
Visit FMU Career CenterFlorence is becoming an increasingly attractive option for remote workers. The city's lower cost of living, short commute times, and location within driving distance of major cities (Charlotte, Columbia, and the coast) make it an ideal base for distributed teams.
Downtown Florence has coffee shops and gathering spaces with reliable WiFi — making it an easy city to stay productive without being tied to a traditional office. There are coworking options emerging, and the overall pace of life supports productivity without the distractions of a major metro.
Lower Cost of Living
More house for your money
Short Commutes
Minutes, not hours
Central Location
Easy drives to major cities
Florence has solid workforce development infrastructure for people looking to upskill or change careers.
Offers technical degrees, certifications, and workforce training programs across healthcare, IT, trades, and business. FDTC is the region's primary source for practical, job-ready skills.
FDTC students and alumni can search and apply for jobs exclusively posted for the FDTC community through the FDTC Career Services portal .
Four-year degrees and graduate programs with strong ties to the local employer community. FMU offers day, evening, and online courses to fit working adults' schedules.
Free career coaching, resume help, and skills training for eligible job seekers. SC Works partners with local employers to provide training programs that lead directly to jobs.
Florence isn't a city where you come to coast. It's a city where your dollar goes further, your commute stays short, and you actually have time to build the life you're working toward. Whether you're job hunting, switching careers, or bringing your remote work here — the Pee Dee has room for you.
Submit your open position and we will list it here for free. HelloFlorenceSC.com is committed to connecting Florence residents with local opportunities.
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